Who's eligible

You are generally eligible to participate on the first day of the month following your hire date after you meet the following eligibility requirements:

When participation begins

For employees first hired on or after January 1, 2018, you will be automatically enrolled in the Plan at a three percent (3%) deferral percentage within sixty (60) days of satisfying the Plan's eligibility requirements unless you affirmatively decline or opt out of the automatic enrollment.

Note: legacy Quintiles and IMS employees subject to the automatic deferrals under one of the respective 401(k) Plans prior to 2018 will continue participating subject to the automatic deferral rules and deferral percentages in place at the time of the merger unless an affirmative election is made to change.

Contributions

As a participant, you can make five types of contributions:

The total contribution percentage cannot exceed 50% in aggregate for Pre-tax, Roth or After-tax.

The company can make two types of discretionary contributions:

Participants who are automatically enrolled in the Plan (as of January 1, 2018) will have their deferral percentage election automatically set at three percent (3%) but may change future deferral percentages at any time after being enrolled, including reducing their deferral percentage to zero. Automatic deferrals will be invested in the Vanguard Target Retirement Trust Plus Fund nearest to the date you will attain age 65 unless you make an alternative investment fund election. You may change your investment fund elections at any time. (Note: Legacy Quintiles 401(k) participants automatically enrolled at the six percent (6%) rate in effect under the Quintiles 401(k) will continue to defer at that rate after 2017 unless they make an affirmative change.)

Vesting

You are always 100% vested in your 401(k) elective contributions (including both regular pre-tax deferrals and Roth post-tax contributions), automatic deferrals, rollover contributions, and any after-tax contributions. You are generally 100% vested in company matching contributions after two years of service and company profit sharing contributions after six years of service. You are partially vested with fewer years of service. See "Vesting in Company Contributions" for more information.

Your accounts

Your accounts are held in your name by the trustee (Fidelity), including your contributions, company matching contributions, profit sharing contributions and any rollover contributions.

Your retirement dates

You are eligible for normal retirement at age 65 and for early retirement at age 55 with five years of service.

Forms of payment

Your 401(k) accounts will generally be paid as a lump sum distribution following termination or retirement. The Plan permits certain post-termination distributions to be made in installments rather than a lump sum and provides for in-service distributions upon attaining age 59-1/2. (The installment and in-service distribution options are new for legacy Quintiles 401(k) participants.)

Note: certain exceptions and grandfathering provisions may apply to Participants entitled to installment or other distributions under 401(k) plans of Participating Employers acquired by the legacy IMS and Quintiles groups. In addition, legacy Quintiles 401(k) participants with QINC and Innovex Transfer Accounts may be subject to special Qualified Joint and Survivor Annuity ("QJSA") distribution options. If you have questions regarding particular distribution options in connection with your participation in prior plans, you may contact the Plan Administrator for additional information.

When payment is made

You can generally elect to receive your account balances:

(Note: other distribution options may be available for Qualified Reservist Distributions as well as for certain nonelective employer contributions, if applicable. In addition, other distribution options may apply to certain legacy accounts under plans of predecessor employers, including the Innovex Transfer Account, the Scott-Levin Transfer Account, the QINC Transfer Account, and certain accounts under the Cegedim 401(K) Plan and the Synavant 401(k) Plan. Please contact the Plan Administrator if the above are applicable and you have further questions about available distributions.)

If you leave before you retire

You can elect to receive your account balance; however, if you are younger than age 59-1/2 and you are not disabled, you will generally have to pay a 10% early withdrawal penalty in addition to applicable income taxes unless you roll over the amount to an Individual Retirement Account (IRA) or another eligible retirement plan.

If you die before you retire

Your spouse or designated beneficiary (requires spousal consent) will be entitled to a benefit equal to the value of your account balances.

Loans

You may take a loan out against your vested account balances, up to the lesser of: (1) $50,000, reduced by your largest outstanding loan balance during the twelve month period prior to the date of the loan; or (2) 50% of your vested account balance. The minimum loan amount is $1,000 and you may have only two loans outstanding at a time.

(Note: Legacy IMS 401(k) Plan participants who had three plan loans outstanding at the time of the merger may continue to maintain three plan loans but are required to pay off at least two of the loans before they are eligible for another loan and will thereafter be limited to a maximum of two loans.)

Hardship Withdrawals

In certain cases, you can withdraw money from the Plan. If you meet the requirements of a qualified financial hardship you may withdraw amounts up to the amount needed for that hardship (with taxes and penalties) based on the Internal Revenue Code Safe Harbor guidelines.